Chronic kidney diseases mostly associated with anemia and electrolyte imbalance. so if you make intervention to treat anemia and/ or electrolyte imbalance (calcium/ phosphate), you can improve the symptoms of chronic kidney disease.

These links may help you

http://emedicine.medscape.com/article/1389854-overview

https://www.niddk.nih.gov/health-information/kidney-disease/chronic-kidney-disease-ckd/anemia

https://www.ncbi.nlm.nih.gov/pubmed/19018744

http://www.livestrong.com/article/298392-electrolyte-imbalance-in-kidney-failure/

Pharmacist based interventions have effectively improved management of hypertension and well-being of the patient.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405859/

Psychological intervention to improve the symptoms of chronic kidney disease

Chronic kidney disease is a multifaceted problem having both physical and psychological connotations for the patient. A multidisciplinary team effort is often needed in the management of such patients. Mental health professionals may need to collaborate with nephrologists for a holistic management of such patients. The patients suffering from renal failure often present with unusual psychological problems where treatment methods vary on an individualized basis and drug therapy is often needed in the management of such problems.

Psychosocial Interventions for Depressive and Anxiety Symptoms in Individuals with Chronic Kidney Disease: Systematic Review and Meta-Analysis

Patient's perceptions of chronic kidney disease and their association with psychosocial and clinical outcomes

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468538/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813124/

http://journals.sagepub.com/doi/full/10.1177/0004867414528589

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886910/

Supporting the emotional and psychological needs of end-stage

renal disease patients

Thank you for your response Mohamed. In my opinion Psychosocial interventions and inclusion of palliative care into nephrology services can be effective.