I'm looking for a tool to evaluate the risk of bias in... Are there any recommended applications or platforms?

More Daniel Sepúlveda-Crespo's questions See All

In PRIMER, is it possible to downweight certain taxa in multivariate community datasets to reflect uncertainty around identification??

I have a dataset with about 80 different species. As usual, some species are very easy to identify with certainty whereas others are more difficult, which means that I am less certain of my...

03 March 2021 8,066 4 View

Which database would give me this list of chemical components?

Dear colleagues: I would like to know if anyone knows of a database that gives me the parameters pH, K, K, Mg, P, C, N, Zn, Cu, Ni and Cd of common foods. I find a lot of information of proteins,...

26 February 2021 5,525 3 View

When I mix oil and NaOH solution, Why solid layer in the surface is formed?

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22 February 2021 2,116 4 View

Rearranging abbreviation list in LaTeX ?

Hi, I'm trying to rearrange an abbreviation list for a manuscript such that it would be listed in alphabetical order. Is there a function that does this automatically or is manual my only option?...

18 February 2021 4,870 2 View

Person-Codes for questionnaires in longitudinal studies: Is there an easy solution for better matching-rates?

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17 February 2021 3,075 4 View

How to fix weka classification errors?

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How to measure the concentration of a labeled protein with no tryptophan or tyrosines?

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04 February 2021 4,482 4 View

Is the use of "multivariate " or "multivariable" was correct in multiple responses study ?

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04 February 2021 7,407 7 View

How do microbes tell the presence of an inorganic minaral in the soil?

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03 February 2021 4,630 10 View

Do you have any suggestion for multicriteria decision-making software?

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25 January 2021 2,454 4 View

How to compare two groups with only two measurements?

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Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence?

I am on the lookout for the Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence. Does anyone know where I can find it? Thank you in advance

03 March 2021 3,568 1 View

What kind of fluid could I use for a pitfall trap that also does not invalidate molecular testing?

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03 March 2021 5,978 5 View

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10?

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03 March 2021 1,401 3 View

I got 02 moderator values defining Johnson-Neyman significance regions. Is it an error?

Hi everyone, I am conducting research for my Master's thesis. I am using PROCESS by Johnson-Neyman to analyze my Moderator model. I test the relationship between Public Service Motivation and...

03 March 2021 2,350 2 View

Do we need to write protocol for a second study of a systematic review that has been registered and published?

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How to increase a model accuracy ?

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Do I need to do linear regression before running mediation analysis using PROCESS MACRO by Hayes ?

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02 March 2021 4,359 3 View

Sample dilution for quantitative analysis using ELISA?

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02 March 2021 7,670 3 View

Is There Any Feasible Method To Test Fluorescent Compounds Other Than Fluorescence Spectrometers ??

Is There Any Feasible Method To Test The Efficiency Of Fluorescent Compounds Other Than UV Spectrometers ? Suggestions Would Be Appreciated !

02 March 2021 5,785 3 View

Heba Ramadan

You can make modification of some tools like QUIPS or ROBINS-I to fit the specific characteristics of your included studies then document any modifications made to the tool in your systematic review protocol or methods section. Describe how and why specific domains were adapted to suit your study characteristics.

Aisha Ejura Dahunsi

Dear Researcher,

Thank you for your inquiry. Based on your description, I recommend using the Risk of Bias in Non-Randomized Studies of Interventions (ROBINS-I) tool to evaluate the quality and risk of bias in the selected articles. Although designed for non-randomized studies, ROBINS-I is applicable to diagnostic accuracy studies and can be modified to suit your needs.

Alternatively, you may consider adapting the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool specifically designed for diagnostic accuracy studies. However, please note that QUADAS is primarily intended for evaluating diagnostic performance parameters, which is not the focus of your review.

To modify any published platform, I suggest consulting the original authors or developers of the tool and seeking their guidance on adapting it to your specific needs. You may also consider consulting with a methodologist or statistician experienced in diagnostic accuracy studies to ensure appropriate modifications.

Best regards, Aisha Ejura Dahunsi.

Yousif Abdulraheem

Possible Modifications:

Domain 1: Patient Selection (or "Sample Selection" in your case):Focus on whether the selection of samples was appropriate for the type of pathogen being tested, considering biases in sample type (e.g., environmental, biological) rather than patient populations.

Domain 2: Index Test (Diagnostic Systems in your case):Assess the methodology of the diagnostic systems in terms of consistency, reproducibility, and any reported limitations in the materials and detection limits.

Domain 3: Reference Standard:Since no gold standard is used, this domain can be excluded or simplified. You may instead assess how well the studies justify their chosen detection limits and materials.

Domain 4: Flow and Timing: Adapt this domain to focus on the reproducibility of experiments and whether the studies adequately describe the processes and conditions under which the tests were performed. Regards