In the central dogma, does translation of an mRNA start before its transcription is finished?

06 June 2015 1 6K Report

I'm wondering whether, in the central dogma of DNA-[transcription]->RNA-[translation]->Protein process in Biology, whether it happens in such a way, in any organism, that the translation to a protein of a specific mRNA strand starts before its transcription is finished?

That is, that the mRNA strand is simultaneously connected to the trasncription, and the translation machinery (on each side of the nucleus wall, I assume)?

Samuel Lampa

Ah, well, found the answer now ... this process happens in bacteria, while in eukaryotic cells, the splicing step required before translation prohibits this from happening (see link).

http://www.nature.com/scitable/topicpage/simultaneous-gene-transcription-and-translation-in-bacteria-1025

Badges
Science topic

More Samuel Lampa's questions See All

Suitable agent based modeling framework for learning ABM in biology?

What is a suitable ABM framework for learning? That is, something where you can quickly get up to speed and play around with it, to get a feel for how ABM works. It has to be suited for...

02 March 2013 5,339 36 View

Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence?

I am on the lookout for the Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence. Does anyone know where I can find it? Thank you in advance

03 March 2021 3,568 1 View

New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before?

Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...

02 March 2021 3,024 2 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Where to find data on trees in tropical agroforestry?

Hi, I'm looking for data (mainly related to management: growth rate, canopy size, soil and climate preferences, etc.) about tropical trees used in tropical agroforestry. Have you ever heard about...

28 February 2021 7,356 8 View

What's the concentration recommend for recombinant protein use in western blotting?

I'm currently working having problem with the concentration for recombinant protein use in western blot, the one been used is Recombinant Human CD19 Fc Chimera Protein-rndsystem which does not...

24 February 2021 8,514 3 View

How to culture mouse pheochromocytoma cells (MPC)?

Hi Everyone, Has anyone here worked with MPC cell line? Any tips or tricks? I am just venturing into cell biology and any advice on this topic would be highly appreciated. Thank you so much. Niusha

22 February 2021 3,891 2 View

How to make a binary prediction based on several experiments runs which contains time series data?

Hi , I am fairly new to machine learning in general. But recently I stumbled on an interesting project . The project is based on the data from...

22 February 2021 3,470 3 View

How to convert 2D stack images to 3D to obtain surface area of nucleus?

I have 15 slices of the nucleus at different z-heights from confocal imaging. I would like to use these slices to reconstruct the 3D nucleus and ultimately estimate the surface area of the...

20 February 2021 6,967 1 View

I can detect my protein but the encoding DNA sequence has stop codons within. Should I ignore the stop codons?

I constructed a synthetic DNA library (scFv, VH-VL orientation) with a 3' reporter and 8x histag. I cloned and expressed this gene following which I performed an ELISA. The ELISA results suggested...

19 February 2021 7,006 5 View