Emphysema is categorised as COPD as you know. Can immunotherapy resolve or reduce its symptoms and severity?
There are modern standards for the therapy of patients with chronic lung diseases. Please study the detailed manuscript in Attachment. You will have a real judgment on the tactics of COPD.
emphysema is a destructive process of the lung either as a primary disease or as a cosequence of hazardous environmental exposures like tobacco smoke and allergic inflammation have no deal in the pathogenesis of this type of COPD . Immunotherapy is a proess to lower the sensitization to a given antigen and it's main task is reducing IgE response to an antigen ( allergen) and also to prevent developing new sensitizations and also preventing asthma.
Hi Ramin
I think immunotherapy is complementary medication in emphysema in comparision with asthma.
Your question has novelty... so I congratulate you!
Please take a look at this useful link.
https://erj.ersjournals.com/content/44/Suppl_58/P3473
I do not see how immunotherapy can help people with this disease. I doubt if any treatment can reverse this damage to the lungs. Even in cases of inherited disease known as alpha 1-antitrypsin deficiency, I still do not see how immunotherapy would help. In the genetic condition, the body fails to make enough of the protein; alpha 1-antitrypsin (AAT), which is supposed to protect the lungs from damage by enzymes. When levels of AAT are low, the lungs become prone to being damaged by these enzymes. Still, I appreciate the question and could spur up very meaningful research in this area. Cheers!
COPD is an obstructive condition and is not categorized among eosinophilis inflammatory
At the other hand immunotherapy is the definitive treatment for allergic inflammation like allergic rhinitis or allergic asthma with an eosinophilic basis.
COPD is an irreversible condition and it's management include chest physiotherapy, antibiotics, LABA, anti-muscarinic anticholinergics and monitoring of the pulmonary function to maintain the condition in a relatively stable condition and prevent it's progression to end stage respiratory failure. Emphysema is a well known complication of COPD due to parenchymal destruction and occurs when the management is suboptimal.