Greeting..
I'm working on improving a formulation of chitosan microparticles are produced via spray dryer. The polydispersity index is still high, by adding surfactant (Tween 20, Tween 80, Span 80) even with small amount the produced microparticles were accumulated on the wall of the cyclone.
I hope my question is clear.... thank you for your help
Check https://www.researchgate.net/publication/10929435_Optimizing_formulation_factors_in_preparing_chitosan_microparticles_by_spray-drying_method
https://www.frontiersin.org/articles/10.3389/fphar.2021.732954/full
Also check https://www.mdpi.com/1424-8247/15/1/54/pdf
https://www.hindawi.com/journals/ijce/2011/267218/
Also check on this
https://www.scielo.br/j/qn/a/fjDw6KVgBPtPRVqsgHWDpVm/?lang=en&format=pdf
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