it is very interesting question,
I think Exercise should be the next option along with treatment.
Hello Sir,
First of all, its a valuable discussion for both patients and researchers. Diabetic people with insulin resistance, also known as impaired insulin sensitivity, have built up a tolerance to insulin, making the hormone less effective. Scientists are beginning to get a better understanding of how insulin resistance develops but still it is something of a mystery. However, recent studies shows that there are some ways to make the body cells more receptive to insulin. Getting active is probably the best way; exercise can dramatically reduce insulin resistance, in both the short and long terms. Furthermore, weight loss can also cut down on insulin resistance but it may not be possible to defeat insulin resistance entirely.
With Regards
Dharmendra Arya
Dear Sir
I totally agree with lifestyles changes (diet and exercise). It depends on the type of insulin you can shift to other insulin (whale insulin or analogues are options). New injectable therapies like GLP-1 like agonists (Liraglutide, Dulaglutide, or Semaglutide) alone or in combination with insulin are very effective and they have the advantage of weight reduction and cardio-protective effects. Oral formulations (Semaglutide) are on the pipe and proved to be effective.Combination therapies (Twincretin, GIP&GLP-1 and other combinations are promising). Stem cell transplantation with its all road blocks could be a choice if all modalities fail.
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