Blood cancer is a very dangerous disease. Blood can circulate to all parts of the body. Blood cells are generated in the bone marrow. So I decided that I work on both blood and bone cancer and collectively hybrid cancer. I need data set of both of these types of blood cancer collectively or separately. I want to research the base of genes by the use of Artificial Neural Networks
Dear Younas Masih,
I do not understand your questions.
There is no "hybrid cancer" between blood cancer and bone cancer.
Best regards,
Thomas
Hello Younas Masih
It is not the right choice. You need to work on blood cancer and bone cancer separately.
The bone is made up of compact bone, spongy bone, and bone marrow. Compact bone makes up the outer layer of the bone. Spongy bone is found mostly at the ends of bones and contains red marrow. Bone marrow is found in the center of most bones and is the soft, spongy tissue that has many blood vessels. There are two types of bone marrow: red and yellow. Red bone marrow contains blood stem cells that can become red blood cells, white blood cells, or platelets. Bone marrow makes nearly all the components of your blood responsible for creating billions of red blood cells daily, along with white blood cells and platelets. Bone marrow also stores fat that turns into energy as needed.
A blood cancer is a disease in which abnormal blood cells reproduce rapidly and begin interfering with the body’s usual operations. Cancers of this type originate in the bone marrow, where red blood cells, white blood cells, and platelets are produced. There are three primary blood cancers: leukemia, lymphoma, and myeloma.
You may refer to the article below for the genes related to hematologic malignancies.
https://ashpublications.org/blood/article/130/4/424/37108/Genetic-predisposition-to-hematologic-malignancies
On the other hand, bone cancer is an uncommon type of cancer that begins when cells in the bone start to grow out of control. The cause of most bone cancers is unknown. A small number of bone cancers have been linked to hereditary factors, while others are related to previous radiation exposure. Primary bone cancer is cancer that forms in cells of the bone. Some types of primary bone cancer are osteosarcoma, Ewing sarcoma, malignant fibrous histiocytoma, and chondrosarcoma. Secondary bone cancer is cancer that spreads to the bone from another part of the body (such as the prostate, breast, or lung).
You may refer to the article below which has summarized the whole genome and/or whole exome genomic studies and placing these findings in the context of genetic hallmarks of somatic mutations and mutational processes in human osteosarcoma.
Article Molecular genetics of osteosarcoma
In the following paper, the authors go on to enumerate the genetic and epigenetic defects identified in osteosarcoma.
Article Osteosarcoma Genetics and Epigenetics: Emerging Biology and ...
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