I want to check antimicrobial activity for novel chemical comp. Apart from MIC &MBC, is there any recent technique to show that activity?

Karthiga Arumugasamy @Karthiga_Arumugasamy

09 September 2012 1 4K Report

P-Phytopharmacology

Evaluation of Antimicrobial Activity of Ruta graveolens Stem

If you want to get a picture of structure activity relationship, that is quite not possible with MIC & MBC data. For a medicinal chemist IC50 or EC50 values will be of greater use as it provides vital information on the effect of substitution upon its activity. This information is quite important for further lead optimization strategy.

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