My protein is metalloprotease (protease that need metal to be active) and the ligand or the other protein is vicillin (I made the model use Modeller and 2cav for template).
If I stir it at high temperature, I notice a gel like layer at the top, if it wasn't heated, there are 2 layers.
05 March 2024 7,346 2 View
The Tianjin-Yonghe's cable Bridge in china The repair of this bridge was done between 2005 and 2007
07 January 2024 3,940 0 View
Any structures like the bridge, building,..... It is better if the structure is reinforced concrete. For damage detection using machine learning.
15 September 2023 4,129 3 View
I will do qPCR from DNA genome. My DNA concentration is only 2-0.5 ng/uL. What is the minimum concentration of DNA template for qPCR? If need more DNA concentration, what should I do? Thank you...
06 July 2023 336 2 View
I want to know the Relative abundance of Antimicrobial Resistance Genes by qPCR (I Will compare the abundance of ARGs and the abundance of bacteria in my sample). I Will use ARGs primers and 16s...
10 June 2023 4,248 1 View
I made detection primers to detect Antimicrobial Resistance Genes in soil that I used in conventional PCR. But, my primers have different results in different soil samples (I extract DNA in the...
08 June 2023 1,639 2 View
I wanna make detection primer of AMR that I'll be used to detect AMGs in soil in bacteria. How to make the primers?
08 June 2023 3,164 0 View
I have 15 samples. 10 samples I measured with XRF and others I used AAS. Can I analys both of them with one analysis or I should measure all of them with one device (XRF or AAS)? I want to know...
04 June 2023 9,045 5 View
I need to know the total of sodium and chloride ions respectively in natural saline soil generally. This is for my thesis and im researching about the effect of salt solution treatment to coffee...
20 May 2023 9,395 0 View
Magic realism
12 January 2023 716 3 View
why don't d-orbitals split themselves because of themselves without the presence of ligands? Electrons are indistinguishable. Why wouldn't it be more correct that protons from a ligand split the...
03 August 2024 3,589 3 View
I'm guessing it's because the ligand experiences too much electron repulsion or proton repulsion from the chromium to insert them close to the 3d-orbitals which are close to the metal nucleus. Is...
03 August 2024 1,370 1 View
Molecular docking software/ websites?
02 August 2024 8,704 7 View
Hello,, The metal complex ligand appears incomplete in the screen of the discovery studio visualizer
30 July 2024 3,354 1 View
Good day, I am a student trying to work on Autodock for a project regarding Ligand-DNA interaction so i am quite new to molecular docking. i have followed tutorials and did all the steps...
28 July 2024 2,136 4 View
I wanted to know whether we can observe the synergistic/antagonistic/additive properties of combinations or mixtures of compounds through docking analysis. But during docking preparation any...
28 July 2024 7,413 6 View
I had a problem for so long. I could easily delete elements in ABAQUS implicit solver but I needed to use VUMAT so I had to have Explicit solution but the element did not disappear for so long. I...
23 July 2024 10,032 0 View
A molecule shows the -11.6 kcal/mol and second one -8.0 kcal/mol so why molecule (A) revealed higher binding score. Please explain major factor involve in it.
21 July 2024 954 5 View
I have performed docking of proteins with two ligands, both ligands show affinity. I want to check the effect if we join both ligands and perform docking
20 July 2024 2,653 2 View
I am performing fluorescence experiments using a ligand to detect metal ions. I want to determine the Lowest Detection Limit (LOD) using the formula LOD = 3σ / K. However, I'm uncertain about...
19 July 2024 1,086 1 View