1. I want to incorporate synthesized Iron Oxide nanoparticles into gelatin gel.
2. When I am trying to make gel it is not forming a homogenous nanoparticles gel as in some part of gel NPs concentration is more and in other part it is much less.
3. Even after I am trying to prepare this iron oxide nanoparticle gelatin gel in ultrasonicator it is not working.
4. I prepared gelatin gel first and then during sonication of iron oxide NPs I took a little amount and add it to gel and after that added this mixture to a 25 ml beaker containing a crosslinker. The gel so formed is not uniform/homogenous.
5. Also I have tried to sonicate Iron oxide NPs first and then add gelatin to it during sonication and then add this mixture to a 25 ml beaker containing crosslinker. Even then the gel so formed is not uniform/ homogenous.
How to troubleshoot this problem and make a perfect uniform/homogenous Iron Oxide nanoparticles in Gelatin gel.
if you want it to foam then you may need to add an emulsifier. you may try adding the gel into a mixture of an emusifier+ FeNPs
You may need to incorporate suitable stabilizer for the gelatin gel. What physical state of NPs do u incorporated in the gel? Is it dried solid NPs or suspension of NPs in aqueous solvent? If it is the former, then u need to modify ur process parameters such as stirring speed, temp., pH, viscosity of the gel. If it is the later, then u have to incorporate suitable emulsifying agent to get a uniform formulation. If u are still not getting the desired texture, then u may consider replacement of the gelatin gel with chitosan or other polymers.
A friend of mine works with iron oxide NPs, he said that they usually aggregate, specially if these NPs are charged, try to use some coating to avoid aggregation. An example of coating is PEG, that lead the NPs to get negative charges, and by Van der Waals forces, they will not aggregate.
- Badges
- Science topic
- Similar topics
- Mathematical Sciences
- Graphs