I did try modified Newcastle Ottawa scale but after removing the comparability of cohorts options, I can score out of 6 only in which most articles are getting only 4 or 5 which is not considered good as you all know. So is there any other tool that I can use or there is no need to do quality assessment in single-arm studies?
There are some critical appraisal checklist that is designed for observational studies.
Please check the JBI critical appraisal checklist for observational studies
here is the link
https://wiki.jbi.global/m/view-rendered-page.action?abstractPageId=9273938
However, In term of assigning the studies with spesfic quality score it is kind of tricky, since they ask questions without giving score, eventually you find your self answering questions (yes, no.. ) without a number to include in your analysis.
However, I have come across one paper which handle this problem in a very nice way.
This is the link for the paper, it is free pubmed paper published in BMC Pharmacology and Toxicology,
https://pubmed.ncbi.nlm.nih.gov/31146791/
This link with similar questions at RG could be useful
https://www.researchgate.net/post/Can_we_do_meta-analysis_of_single_arm_observational_studies
I found one more link
https://www.researchgate.net/post/single_arm_meta_analysis
Ahmed Osman Mohamed and Proloy Barua thank you so much for the help!!
Hi Qazi
Check Modified Black and Downs Guidelines.
It's quite straightforward although it takes into account main domains including external, internal validity and the power of the study.
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