Human genes and disease database

More Ashraf Rangrez's questions See All

Does anyone have experience with Co-IP using multiple antibodies at once?

I would like to know if anybody has ever tried performing co-immunoprecipitation using a mix of two or more antibodies against a partcular protein (I mean not separately, but together in one set...

06 July 2013 1,374 10 View

Consortia of similar journals?

There could be 1000s of journal in the field of biology, which a very broad subject. But certainly there could be limited number of journals for specific subjects e.g. crystallography,...

02 March 2013 7,679 10 View

Journal for microRNA research.

Is there any journal dedicated specially to microRNA research, and accepts research and review articles associated with microRNA?

02 March 2013 3,978 8 View

Paper writing: before or after thesis writing?

Is it advisable for PhD students to write their research articles all at once at the end of their PhD thesis, while or after completing thesis writing or they should be written and published as...

31 December 2012 8,589 91 View

Does knowledge come only with the age or number of years one spends in a particular field?

Earlier I raised one question that what is the impact of a "review article" compared to a "research article" in scientific community. The topic was very well discussed but many of the topic...

31 December 2012 2,971 24 View

Does anybody know a nice working antibody to detect total sumoylation status in the protein preparation from heart or cell lysate?

I want to detect the sumoylation status of protein lysate prepared from mouse tissue and skeletal muscle cell line (C2C12 cells) lysate and I am still trying to figure out which single antibody...

11 December 2012 1,116 4 View

Is it possible that the transcriptional regulation of a given microRNA remains the same in different organs / tissues / cells?

I am wondering if every microRNA is regulated by the same transcription factors and regulatory mechanisms in all cell types it is expressed or every cell type has independent regulatory mechanism...

11 December 2012 6,231 29 View

'Master' miRNA or 'super' miRNA?

miRNAs control various physiological and pathological processes, but what controls microRNAs? What controls their switch-on switch off? Is there any miRNA which can be termed as a "super" miRNA...

09 October 2012 6,004 13 View

Are pri-miRNA and pre-miRNA sequences coding for all validated mature microRNAs known?

There are almost 1000 or more microRNAs known for human / mouse / rat. I am wondering if the pri-miRNA and / or premiRNA sequences of all these microRNAs is also known? If yes, is there any...

09 October 2012 4,144 3 View

Prediction of microRNAs against a gene of interest

I know there are several databases where one can look for the miRNA targets. But does anybody know if there is any database or online tool to identify putative miRNAs against a given gene of...

09 October 2012 8,275 7 View

New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before?

Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...

02 March 2021 3,024 2 View

How does one access the Cranet survey data on HRM practices?

Hello, The Cranet website does not provide any lead to the data obtained from their multinational survey on HRM practices. Any help on accessing the data would be most appreciated. Thank...

01 March 2021 9,536 3 View

Is there any research regarding how training and development is going to change in the era of Fourth Industrial Revolution?

As the organizations getting prepared for the fourth industrial revolution, to enhance the skills of their workforce what type of changes are necessary and going to occur in the training and...

01 March 2021 3,199 3 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Is it possible for two human neuronal cell lines to have different gene sequence for the same protein?

I am looking at the ATP1A2 (Sodium/Potassium ATPase alpha subunit 2) in two human neuronal cell lines. Expression levels of this protein seems to be almost equal when detected by one antibody....

01 March 2021 3,607 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Where to find data on trees in tropical agroforestry?

Hi, I'm looking for data (mainly related to management: growth rate, canopy size, soil and climate preferences, etc.) about tropical trees used in tropical agroforestry. Have you ever heard about...

28 February 2021 7,356 8 View

Genome-wide gene identification protocol ?

Is there any book chapter/book, webpage or research article available to understand genome-wide gene identification?

28 February 2021 8,095 1 View

Any specific pipeline or parameter to analyse total transcriptomics study of brain tissue samples?

I have two groups of brain samples, control and treated for example. It was total RNA nova seq sequencing. I tried all the available pipeline like: star+rsem+deseq2, Hista+stringtie+cuffdiff,...

27 February 2021 356 6 View

How long do vaccines protect us against COVID 19?

Or will we have to get vaccinated every year, as in the case of influenza?

27 February 2021 1,048 5 View