How to run python based apps contain mechanize?

02 March 2016 8,186 2 View

What is best web site for computational resources on Zika Virus?

Presently, Zika Virus is one of the major challenges for mankind. It is important to discover drug, vaccine and biomakers for this disease as soon as possible, in order to prevent its spread. Thus...

01 February 2016 3,632 12 View

May I know your opinion on GPSR package?

We are planning to develop update version of our GPSR package (A resource for genomics, proteomics and system biology). In this package we included most of PERL routine required in bioinformatics....

10 November 2015 2,730 4 View

How fourth paradigm is relevant to your research?

I wants to know need of fourth paradigm in different research fields. In this article, I mentioned how it is important in our area of research. I hope, we are getting big data in other fields...

05 June 2015 2,871 1 View

Is any gene responsible for boredom?

It has been observed that some people feel more bore than others. I have seen some kids who frequently complains that they are feeling bore. I wants to understand what is scientific reason behind...

31 December 2014 782 0 View

Which is best software for mining BIG data?

We are working in bioinformatics and chemoinformatics. We need your help, I will highly appreciate if you suggest best software for mining big data. I will appreciate if you suggest free or open...

11 December 2014 2,576 18 View

How to improve visibility of my research?

This is an important for a researcher that his work is read by users. Publishing paper in a good/popular journal (high impact factor) is first step in research. Next step is to make it available...

10 November 2014 1,934 16 View

Can you provide information on FDA approved peptide based drugs?

Dear Colleagues, we are interested in peptide based drugs approved by FDA so far. We got brief information about these drugs from FDA site, we need more information like amino acid sequence, drug...

09 October 2014 2,600 7 View

Do you think this database for experimentally validated antiparasitic peptide sequences and their structures will be useful?

May I know your comment on this database?

07 August 2014 1,983 2 View

How can researchers contribute to combat the Ebola virus?

As all of us know that Ebola virus is one of the major challenge for researchers community. I hope number of researchers are already working on this dread virus. As well as number of researchers...

07 August 2014 9,310 8 View

Which of the Covid-19 Vaccines would elicit the best immunoprotection and why?

I want to know which of the available Covid-19 Vaccines would elicit the best immunological response and why

02 March 2021 1,388 3 View

Experimental Design: How deal with pseudreplicates with immunological and clinical-chemical paramaeters?

Hello everybody, I am investigating the influence of a toxinon various clinical-chemical and haematological parameters in fish. I have three treatments (control, low dose, high dose) in my...

24 February 2021 1,243 1 View

Looking for advices and tips to improve the staining and the gating strategy in human blood?

Hi, I am staining a human blood with CD19, CD3,CD14 and CD16. My gating strategy in FlowJo goes like this: - First, I gate a general population SSC-A VS FSC-A => Then gate for single cells, =>...

21 February 2021 5,724 4 View

Can you polarize Jurkat cells into different T helper subsets?

I am wondering if anyone has had success with in vitro polarization (via cytokines) of Jurkat cells. My goal is to understand the affect of a drug on Treg induction and differentiation. I...

12 January 2021 3,606 2 View

Can only the spike protein of the virus provide immunity?

Virology, microbiology, immunology, vaccine

21 December 2020 424 16 View

Can somebody recommend me a decent textbook to learn more about signaling pathways and their mechanistic principles in general?

I studied biochemistry and molecular biology in my bachelors and Immunology in my masters. I never came across a suitable course for general signaling pathways and principles. My interest is...

13 December 2020 5,690 5 View

Is it possible to extract DNA or RNA from paraffinized biopsies ?

My lab have some skin biopsies that were previously conserved in paraffine , and i wanted to know if it is possible to extract DNA or RNA from them.

06 December 2020 7,964 6 View

Could the desmin mutation in myofibrillar myopathy be caused by an infection?

A patient with desminopathy (mutation Thr341Pro DES in a heterozygous state) with the progression of the disease has a decrease in taste and smell, immunosuppression, and an increase in IgA in the...

02 November 2020 5,886 6 View

Whis HLA-A2 TAAs are best for DC pulsation and CD8+ cytotoxic T cell induction?

When looking to establish Ag-specific CD8 cytotoxic T cells with autologous dendritic cells, there are numerous tumor-associated Ags to choose from. Does anybody know which Ags give the best...

27 October 2020 2,068 2 View

Resuspending cell pellet after ficoll centrifugation?

In my current project I am planning to isolate mononuclear cells from peritoneal ascites of cancer patients using ficoll centrifugation. However, following isolation of the mononuclear cell layer,...

26 October 2020 5,966 4 View