To set an effective dose for a toxicology experiment, you can use the IC50 or LC50 values. IC50 is the concentration of a substance that causes 50% inhibition of a biological or biochemical function, while LC50 is the concentration of a substance that causes 50% mortality in a population.

To determine the IC50 or LC50 value, you can conduct a dose-response experiment where the substance is administered at various concentrations to a test group, and the effect on the biological or biochemical function or mortality rate is measured. Once the IC50 or LC50 value is determined, the effective dose can be set at a concentration that is slightly below this value.

It's important to note that the IC50 and LC50 values may vary depending on the species, strain, and other factors. Therefore, it is important to conduct the toxicology experiment on the specific organism or cell line that is relevant to your study.

I hope this helps you...

https://www.researchgate.net/post/What_is_the_main_difference_between_IC50_LC50

IC50 (Inhibitory Concentration 50%) is the concentration of drug that is required for 50% inhibition of a cellular process in vitro.

LC50 (Lethal Concentration 50%) is is the average concentration of drug or chemical which is required to kill half of the exposed population of animals or cells in a specific condition

I do not have personal opinions but here is the information on setting an effective dose for toxicology experiments in context of IC50 and LC50.

To set an effective dose for a toxicology experiment, the following steps can be followed:

It is important to note that the effective dose may vary depending on the specific study and the substance being tested, so it is important to consult with a toxicologist to ensure that the dose is appropriate for the study.

thanx Abdullah Khan sir for your valuable answer