How to represent cancer in differential equation model ?

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How to convert a .fasta file to fastq file ?

I have a FASTA file, how can i convert it to a FASTQ file via command line or by any online converter. The existing online converter is giving error and is unable to parse my fasta file.

11 December 2018 10,058 15 View

How to construct a 5-node PPI-TF-mirna-gene regulatory network?

I have some genes known to be involved in Oral Submucous Fibrosis (OSF) progression and also their PPI network along with gene-gene interaction. I want to construct a 5-node Feed forward loop with...

09 October 2018 1,876 0 View

How to map Illumina probe set ID to Gene ID?

Is there any computational tool/software/program code to convert/map illumina probe set IDs to gene IDs for a large data file...

09 October 2017 9,940 1 View

How to extract or unzip HT_HG-U133A files for further anlysis of gene expression data?

I have HT_HG-U133A and Normalized gene RNAseq data, but both in zipped format.When i unzip them they are not opening with any softwares . How should i make useful for further gene expression...

07 August 2017 1,085 3 View

What is the best approach for detecting functional modules in gene expression data ?

What are some of the best approaches to find out functional modules in gene expression data .

04 May 2017 8,040 4 View

How DNA Circuits be used to stop cancer progrssion?

Can DNA Circuits be used to make nano auto triggered bombs to stop cancerous cells from growing when they come in contact with them.

08 September 2016 2,643 1 View

How can Q3 accuracy of secondary structure of proteins be calculated ?

How is the Q3 accuracy or three state accuracy of secondary structure of proteins calculated. In some texts it is written that it the no. of correctly predicted secondary conformation of amino...

02 March 2016 1,184 5 View

Is Python better than Perl ?

Which scripting language is more powerful for developing bioinformatics applications / tools ?

08 September 2015 8,814 2 View

Does drinking excess coffee prevent sleep paralysis ?

Does excess coffee concentration acts like a drug to reduce our sleeping habit .

08 September 2015 5,865 4 View

How much voltage is generated in brain when synapse occurs ? Is it sufficient to light up a bulb ?

How does electrons flow from one synaptical area to another during synapse ?

08 September 2015 3,844 1 View

How can I prepare virus for a TEM or SEM imaging?

I have virus (viral hemorrhagic septicemia virus) in suspension and the experiment will not involve cells. What level of TCID50 is preferred?

11 August 2024 3,115 1 View

Request a single Lecture notes for math as detailed as this that I can find in one place?

- The Existence/Uniqueness of Solutions to Higher Order Linear Differential Equations - Higher Order Homogenous Differential Equations - Wronskian Determinants of $n$ Functions - Wronskian...

03 August 2024 2,366 0 View

Is it necessary to covary exogenous constructs in a structural model?

I am working on a SEM model where i have 7 latent variables (6 exogenous and 1 endogenous). In AMOS when I co-vary the exogenous constructs, only 2 paths are coming significant out of 6. But when...

03 August 2024 6,028 4 View

Radiogenomics Cancer Research Challenges?

what are the top 3 challenges to the advancement of the field of Radiogenomics in cancer research? is it the availability of easily available low-cost matched imaging and biosamples with clinical...

03 August 2024 5,828 4 View

What is the acceptable p-value cutoff for GO enrichment analysis ?

I have an RNA-seq data that I have analysed using Limma-voom and have extracted the gene IDs, log2FC and the p-values. At p value < 0.05, I have over 10,000 DEGs, however, when I run the GO...

31 July 2024 225 2 View

In SEM, if a latent variable consists of three observed variables, and each observed variable has four items, what should I do?

Suppose I am studying the construct of "Academic Motivation" (latent variable) in students, which is measured through three observed variables: "Intrinsic Motivation," "Extrinsic Motivation," and...

31 July 2024 3,913 6 View

Bootstrapping in SEM Amos ?

Can a researcher use small sample size of 40 while using SEM with bootstrapping of 1000 and is it possible to get published

28 July 2024 4,402 2 View

Can we find a statistical matrix mechanics equivalent to the Schrödinger equation?

We assume that we can find a statistical matrix mechanics equivalent to Schrödinger's PDE in two consecutive steps: i-Transform the Schrödinger PDE describing the wave function Ψ into its square...

27 July 2024 3,959 4 View

Does it exist some special technique for cutting ceramic membranes for Cross-sectional FESEM images?

Does it exist some special technique for cutting ceramic membranes for Cross-sectional FESEM or SEM images?

25 July 2024 5,482 2 View

Seeking MATLAB Code for Differential Evolution in Multilevel Thresholding Image Segmentation ?

Hello, I am a research scholar currently working on a project involving image segmentation, and I am interested in using differential evolution for this purpose . I would greatly appreciate it if...

25 July 2024 9,926 1 View