How to prevent the lymphoma development in the xenograft models in NOG mice?

16 March 2019 0 2K Report

I have performed patient-derived xenograft model (PDX) using NOG mice.

3 out of 10 mice in which tumor has grown has been shown to be malignant B cell lymphoma positive for CD20.

Several papers indicated that Epsteiin-Barr virus infection is responsible for lymphoma development in this immunodeficinet mice.

Therefore, I would like to know how to prevent the lymphoma development in the xenograft models in NOG mice?

Thank you in advance.

Badges
Science topic

Similar topics
Phytochemistry
Extracts

More Go J Yoshida's questions See All

Who of all of you will help TPEOM to re-originate the Earths atmosphere to it original 5 atmospheric elements/gases?

Global ‘Weather’ has stopped, as ‘aqua thermionic instituted by the ‘Global thermo atmospherics has instituted global thermodynamics of 120º C + and thus all waters are, or have boiled into a...

06 August 2024 8,716 0 View

Who of all the Global Scientific community will help me Prof. Dr. Yoshida make way for TPEOM, MEC ~EMC to return the atmospheric gases to the norma ?

TEP presentation caption (The Environmental Project) Re: Why should Washington’s DC, or any country government point of location think of as nowadays of as to being 'tomorrow as to come! if it...

03 August 2024 2,484 1 View

Hi, could anyone suggest me drought tolerance index for conifer species seedlings? I only get literature about drought tolerance index for crops?

can we use crop drought tolerance indexes for conifers as well?

25 March 2024 6,365 1 View

What is your answer, decision for this?

Who of all of you that see, read this will make action' with me to save this world from its NOW happening global thermodynamics of of a very bad exterminating start of 01/05/2047, and into a...

09 March 2024 1,041 18 View

How to deal with TRIzol aerosolization during FACS Sorting directly into TRIzol?

I am currently collecting 1k-100k cells through FACS sorting for qPCR and RNA-seq. Several online protocols suggest sorting cells directly into TRIzol, and I have found this method effective for...

15 January 2024 2,002 2 View

What is the difference between single valid assignment and multiple assignment in mass spectrometry?

05 November 2023 6,853 1 View

What are the different ways to simulate FRCM composite plates in ABQUS??

FRCM (Fiber-reinforced cementitious matrix)

06 August 2023 7,907 0 View

What do two lines in FSC-A and FSC-H plot indicate in flow cytometry?

I am studying lymphocytes in the spleen using flow cytometry and I am trying to discriminate doublets in the FSC-A and FSC-H plot. In my data, there are two lines gated as P1 and P2. How should I...

18 February 2023 6,321 7 View

Anesthesia mumps confirmed by CT as pneumoparotid?

I would like to ask anesthesiologists or clinicians who have experienced anesthesia mumps. Was there a case in which the swelling of the parotid gland is associated with a retrograde insufflation...

08 November 2021 312 1 View

How can I identify the domains of a protein whose 3D structure is predicted by AlphaFold?

I used AlphaFold to predict the structure of a protein that has not been well studied. I have a pdb file of the predicted structure. Now I would like to identify the domains of the protein using...

31 October 2021 1,532 12 View

How can I prepare virus for a TEM or SEM imaging?

I have virus (viral hemorrhagic septicemia virus) in suspension and the experiment will not involve cells. What level of TCID50 is preferred?

11 August 2024 3,115 1 View

Why Do TDS and EC Increase with Larger Wastewater Volumes, While BOD and COD Decrease?

I have carried out MFC experiments on three different volumes, 50, 500 and 1000 mL of wastewater. Results after MFC treatment shows that TDS and EC are more in larger volumes of water i.e. TDS and...

09 August 2024 9,621 0 View

Could it be a cell culture contamination?

Hello everyone! I observed in my culture (htert-RPE1 cells) an orange- red particle at the bottom of the dish. It is visible to the naked eye as a very very small red dot. Could it be a...

09 August 2024 2,824 3 View

Is there any way to quantify bacterial and fungal cells in their mixed culture?

I am working in fungal fermentation of soybean meal and there is bacterial growth in them at times. I am trying to quantify fungal cell counts and bacterial cells; but I haven't been able to do at...

07 August 2024 7,535 4 View

How to normalize and take the significance of the MTT OD values with 3 replicates for the same cell-line?

Hi, I have a question about normalizing the MTT OD values for doing the statistical analysis. So, if we have 3 different plates and we call them 3 different replicates, so, first we would...

07 August 2024 8,106 4 View

Why activated CAR-Jurkat cell could not kill targets?

Previously when I co-coluture anti-CD19(FMC63) CAR-Jurkat with Raji with E:T=5:1, Jurkat can eliminate Raji in 24h. However, when I test another CAR construct, although I can dectect totally CD69...

06 August 2024 641 2 View

How to report results of Generalised Linear Mixed Models in a journal article?

Hi everyone, If you have written or come across any papers where Generalised Linear Mixed Models are used to examine intervention (e.g., in mental health) efficacy, could you please share the...

04 August 2024 4,130 4 View

How to isolate lymphocytes from mouse spleen?

I have tried several times to isolate lymphocytes from mouse spleen, but all attempts have been unsuccessful. I tried most available protocols. I used different dissociation media (HBSS with Ca...

04 August 2024 9,913 7 View

How to Add Missing Water Molecules in Protein-Membrane Simulations?

I have protein-membrane simulations (PDB, PSF, DCD) and have noticed that water molecules near the protein are not visible in the simulations. How can I fix this issue? Is there a way to place the...

04 August 2024 1,200 2 View

Does long-term culture of murine Monocytes result in macrophage differentiation?

Hi, I am isolating monocytes from the bone marrow using the Mouse Monocyte EasySep kit. I want to treat these cells and monitor expression of specific markers over the course of 10 days. I will...

04 August 2024 7,282 2 View