Solubility of Uric acid is very low in Saline or water, it needs to be prepared with a very high amount of NaOH to get to pH of around 13, but every article we found talked about preparing Uric acid in saline to be given to animals intraperitoneally (250mg/Kg/mouse). Any suggestion? Can we inject a high alkaline solution of pH13 into animals? can we inject to intraperitonial not soluble Uric acid?