Hello Ümran,

according the potentially useful link cited below, PLA (= polylactide or polylactic acid) is (citation) "typically dissolved in HFIPA, Chloroform, or THF depending on the degree of crystallinity." HFIPA is hexafluoro-2-propanol, but this fluorinated solvent is not easily available to many researchers. Thus in your case it might be worth trying chloroform. Short sonication in a normal ultrasound cleaning bath could also help obtaining a clear solution. Please have a look at the following guide:

Advanced GPC Analysis of Polylactide

https://www.hmjassociates.com/uploads/8/9/1/7/89179772/hmj_gpc_app_note_7_-_pla.pdf

Good luck with your work!

Dear Ümran Aşçı,

For GPC analysis of PLA, Dissolving in Chloroform is the simplest way.

Hi Ümran Aşçı . See the following link: https://www.google.com/amp/s/blog.sepscience.com/liquidchromatography/understanding-gpc/sample-preparation-in-gpc/sec%3Fhs_amp%3Dtrue

See the following link: https://www.mdpi.com/1422-0067/21/1/77/s1

Also see the following link: https://www.google.com/amp/s/www.azom.com/amp/article.aspx%3FArticleID%3D13673

Kindly see also the following link: https://www.sciencedirect.com/topics/materials-science/gel-permeation-chromatography

Dear all, additional details are given in the following RG thread and the attached file. My Regards

https://www.researchgate.net/post/How_can_I_analysis_GPC_for_Poly_lactide2

Hi..

The dissolving solvent for PLA is chloroform, and the column is different for each solvent.

An excellent column for detecting PLA is a column for Chloroform.

Dear Umran

https://www.researchgate.net/profile/Abdelkader-Bouaziz/post/How_to_prepare_a_solution_for_GPC_analysis/attachment/61814ddcb3729f0f61907830/AS%3A1085706579517443%401635864028724/download/GPC-PLA.pdf

Gel permeation chromatography (GPC) is a analytical techniques for understanding and predicting polymer performance. You can try aetonitrile / chloroform for preparation of sample solution.