How to predict the structure of the outer membrane protein through homology modelling?

Naresh Niranjan Dhanasekar @Naresh-Dhanasekar

17 September 2012 1 251 Report

I am planning to work on the outer membrane protein of a bacterium, which leads to gastroentritis. I found out the best way to target is through the outer membrane protein.

Ricardo J Ferreira

You can do a BLAST search from your FASTA sequence to find similar structures with available PDB. If the similarity gets above 50%, it's a good template for you to build an homology model.

Them, you use MOE or MODELLER to get your homology structure.

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