Hi
I am extracting genomic DNA from dust samples and the 260/280 ratio is 1.4 whereas 260/230 is 1.35. I need to perform the metagenomic sequencing and for the same, the recommended 260/280 ratio should be greater than 1.8. Can anyone help me with how can I improve this. I have tried ethanol precipitation but it causes a significant reduction in the yield. As these are environmental samples the yield of genomic DNA is already low.
Thanks