To use an inhibitor, prepared and sold in a methyl acetate solution, I need to evaporate the aforementioned solvent and exchanging to ethanol or DMSO. I will do that with a gentle nitrogen stream. When it comes to dissolving the inhibitor with the new solvent (2 ml), it is stated that I could use ethanol "purged with an inert gas". Now, the only chance I have is purging with nitrogen (no argon in our lab) but I will cause again a loss of volume. How can I avoid this? By minimizing the flow maybe?
Hi Roberto Boi , I think purging with nitrogen is perfectly OK. Nitrogen is an inert gas like argon. There is no really big difference. You could just take e.g. 10 mL of ethanol and purge it with nitrogen to remove most of the oxygen. Then you can take out 2 mL with a syringe.
And if you needed purged EtOH on demand, you could set up a gas scrubbing bottle fllled with ethanol, purge it then use the alcohol 'saturated' N2 to purge your working EtOH. When the scrubbing bottle is not in ues it can be sealed off.
If you intend to do a lot of work in the absence of O2/CO2 then you would be more comfortable working in a 'glove box'. They are not difficult to make.
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