How to estimate change in gene frequencies in bacteria using evolutionary game theory?

Sreeram Chandra Murthy Peela @Sreeram-Peela

22 December 2017 1 845 Report

Hi,

I would like to derive a mathematical model that can explain the change in frequencies of two genes that cause resistance to a particular antibiotic. Based on the literature, one of the genes is expressed only constitutive, while the other is a membrane protein. I would like to know the methods and protocols to follow for using evolutionary game theory. As I am learning it right now, any reference to similar articles or texts would be much appreciated.

Thanks.

Atin Basuchoudhary

Mcelreath and Boyd's social evolution is a simple yet comprehensive start to help guide you in modeling these evolutionary processes using game theory (http://press.uchicago.edu/ucp/books/book/chicago/M/bo4343149.html).

Gintis's book "Game Theory Evolving" (https://press.princeton.edu/titles/8900.html) is a slightly more advanced but also easily accessible book. The topic is covered in two chapters on evolutionary dynamics.

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