We're working on meta-analysis of studies that provide median OS data. We conducted other meta-analyses using objective response rates (ORR) and used the inverse-variance method. But we're not sure what method to use for OS. I'm comfortable using R on packages like "meta" or "metafor" and I can use a new package if necessary.
Second problem is that some studies did not provide a confidence interval, and I read a systematic review (attached below) and they dealt with this problem by "repeating the analysis 1000 times on a bootstrap sample", I need some explanation on how we can do this.
Thanks a lot!
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