I am going to conduct a perspective study on the title of "Gut microbiome in pregnant women with iron deficiency".
Objectives
The prior studies just only reported the percentage of Gut microbiome types. So we think we are going to determine sample size needed to detect a difference between two proportions. I am not sure if this is appropriate.
When it comes to a cohort study, the sample calculated is a big number. Our concerns are the cost of gut microbiome laboratory and analysis ,time limitation and a small number of eligible participants.
The sample size calculation was not reported in the previous similar studies.
This is some example of the previous studies.
https://www.frontiersin.org/articles/10.3389/fcimb.2021.549678/full
https://www.mdpi.com/2072-6643/15/3/691
Article Gut microbiome profiles in Thai healthy pregnant women and i...
Thank you very much
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