how to calculate power value for Polymorphic studies and how to predict the sample size to get optimum power value ?
What will be the power value for SNP study in Sample size of 30?
05 June 2018 7,072 0 View
when am doing ARMS PCR both WT and MT amplified equally? how to minimize WT amplification?
04 May 2018 8,833 3 View
How a mutation in introns affect the gene expression. if a SNP is not present in any downstream regulatory elements but in somewhere intermediate region of intron and how those polymorphism...
02 March 2018 5,975 3 View
Will the sequence specific primers used for the real time PCR will work with ordinary PCR amplification?
01 February 2015 750 5 View
I would like to design the primer pairs for Monoamine oxidase gene, can anyone suggest me how to get pre designed primers for monoamine oxidase or how to design it for the wistar albino rat from...
01 February 2015 3,691 0 View
Can anyone suggest me how to download full version of ChemBioDraw for free
01 February 2015 1,408 0 View
How can I avoid retention time shift in biogenic amine estimation using a UV-VIS detector even when the temp, pH and column condition was maintained?
08 September 2014 5,139 3 View
I wish to know the concentration or level of all heavy metals in human serum sample and tissue samples according WHO guidelines?
08 September 2014 3,791 8 View
average particle size calculation from TEM
04 August 2024 2,921 1 View
I am following Hainmueller, Hopkins, and Yamamoto's (2014) paper for my randomized conjoint experimental data analysis. The link to the paper is provided below. I received a comment from the...
02 August 2024 4,406 0 View
Is there a straightforward way to conduct a sensitivity power analysis for a Kendall's Tau correlation? I was considering using the sensitivity setting and "Correlation: point biserial model" test...
28 July 2024 6,133 8 View
Genome-wide association study (GWAS) Continuous traits: eg. Height Discrete traits: eg. Eye color
28 July 2024 286 0 View
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24 July 2024 3,087 3 View
I am currently conducting a mendelian randomization study, and I was attempting to use PhenoScanner to look for potential confounders associated with the selected SNPs (any SNPs significantly...
23 July 2024 5,703 0 View
I want to study the differences between two groups: the treatment group and the comparison group. The total population consists of 60000 women in the treatment group, distributed across different...
21 July 2024 669 3 View
I forgot to autozero during the run (Size exclusion chromatography.) and later i realised i forgot to do that and the baseline was not zero but below zero (and in some cases it above zero). I...
15 July 2024 5,551 6 View
I was using Superose6 10/300 Gl column for purification of my target protein. the sample consists of various oligomeric state and i would like to identify the approximate elution volume where my...
15 July 2024 5,157 2 View
We have conducted a systematic review to investigate the effectiveness of a treatment for a psychological disorder. We aim to report effect sizes and p values of the reviewed studies but one study...
10 July 2024 7,186 4 View