How to calculate pecent of injected dose per gram of organ ?

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What is proper injection solvent for drug insoluble in water?

Dear all, I use hydrophobic or insoluble drug for injection What is proper solvent that is low cytotoxicity ?

31 December 2016 2,740 4 View

Oxigen, double bonded to benzene, is carbonyl oxigen?

Dear all, Oxigen, double bonded to benzene, is carbonyl oxigen? (e.g. Phenoxide) Thank you for reading my question.

11 December 2016 9,565 0 View

What is the best solvent for pi-pi interaction of CNT with aromatic compound?

Dear all, What is the best solvent or buffer for pi-pi interaction of CNT? Low polarity solvent is good for non covalent conjugation? I wonder that... Thank you.

11 December 2016 2,081 1 View

Biomolecule and polymer have zetapotetial ?

Deat all, I wonder that biomolecule and polymer have zeta potential. Zeta potential is used in liquid system consisted of collid. So... biomolecule and polymer are colloid?

09 October 2016 10,099 2 View

How nanoparticles bind with thiolated compound ?

Dear all, Thiolated chemicals can bind to nanoparticle covalently (e.g. gold, silver, quantum dot...) and that is well known. But I have question. What is principle or drive force of...

06 July 2016 1,573 1 View

Why use coupling reagent [ex) EDC/NHS] ?

Good afternoon :) I want to bind carboxylic acid-SAM layer with protein having amino group. In too many paper, coupling reagent is used for 'activation'. I know that carboxyl group react with...

04 May 2015 3,417 1 View

Is Osmium tetroxide necessary for SEM?

I want to make cell sample for measuring SEM but I don't have osmium tetroxide ( I heard it is expensive reagent...) I have to use osmium tetroxide? or negligible? Are there any other alternatives?

03 April 2015 5,272 6 View

• What the possible Persistent Organic Pollutants and Heavy metals present in fluorspar, sediments, and water bodies around its mining area?

Approximate concentrations are require in compared with the WHO permissible limts

11 August 2024 2,723 1 View

Basis set and input instruction to calculate HOMO and LUMO using Orca for Imidazolium based organic salts?

Hey there, As a synthetic chemist delving into theoretical calculations for my imidazolium-based organic molecules, I would greatly appreciate any guidance on the appropriate input instructions...

09 August 2024 5,444 7 View

How do I conformally do PR spin coating on trench structure?

I did PR spin coating on trench structure. I used AZ P4620 PR and the thickness or PR is around 11um. The substrate is Si. And my trench structure depth is 141um(negative way). Even though I...

08 August 2024 2,298 0 View

Is changing the medium during the experiment overestimate the results?

I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...

07 August 2024 2,283 2 View

Separation of organic acids-HPLC?

Hello What should be done to separate and identify organic acids in HPC when their RetTime is the same?Like oxalic acid with Propanoic Acid.or acids that have a very close RetTime.

07 August 2024 8,782 3 View

Which solvent is better to dissolve with secondary metabolites extracted from fungi?

I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...

03 August 2024 4,725 2 View

Can i quantify a nanoparticle encapsulated in cell culture medium by hplc?

Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...

03 August 2024 2,730 1 View

How can I find access to heavy metal reference doses from the EPA and WHO websites?

Reference dose and Maximum acceptable concentrations HMs

03 August 2024 8,230 4 View

How to convert g/kg Humic acid dose to kg/ha?

I used humic acid at 0.044 g/kg soil in my pot experiment. But finally, I have to recommend kg/ha. Each pot's soil weight was 11 kg. What is the solution?

02 August 2024 7,186 6 View

How to improve peaks separation in HPLC?

Hi everyone, I'd like to better separate two close peaks coming from a bioconversion sample, I'm currently using a C18 KromaPhase 4,6mm Ø.I. SCHARLAU, particle size (µm): 10, pore size (Å): 100,...

30 July 2024 435 3 View