How to calculate mass of reagents based on desired pH and molarity?

Kieran David Robertson @Kieran-Robertson-4

29 March 2024 1 7K Report

Dear all,

I am looking for guidance relating to a formula to calculate mass of reagents based on the desired pH and molarity. Is there a formula for this?

I am looking to create, and justify with calculations, a phosphate buffer. I am intending to create phosphate buffers 0.1 M pH 6.0 and 0.2 M pH 6.8.

Thank you in advance for any guidance :)

Kieran

Adam B Shapiro

https://www.aatbio.com/resources/buffer-preparations-and-recipes/phosphate-buffer-ph-5-8-to-7-4

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