We are working on blood pressure responses during steady treadmill exercise. Rise in blood pressure occurs during the exercise. So can we use this difference as a Delta or not?
I guess it depends on what kind of changes you are expecting to see, and what type of statistical test you want to be running on it. To expand further, my question is, do you want to compare relative changes (delta) between subjects? or within subject mean? Assuming I understand the question sufficiently (I hope), I think you want to compare means of post and pre, and you have only one group and two time points. In that sense, I think it is possible to measure delta for both systolic and diastolic BP. Many researchers actually use that to determine magnitude of change, which in some cases, may be better than just looking at absolute values.
in our experience it is not possible to calculate the delta and the slope of exercise related blood preassure increase, because blood preassure increase during excersise does not follow a linear function but an exponential function with a individual plateau. Second in endurance athlets sometime the diastolic blood pressure goes down before it increases.
It is perfectly normal to calculate the delta, as in figures 1C and 1F (representing responses in pulmonary arterial pressure) in the paper below.
Expressing the data in this way can give a better idea of the responses from pre to post exercise situation. Maybe it is already your intention: why not taking different time points during/after the exercise? You could get pressure values every minute for example, to study its evolution during exercise, and the recovery pattern afterwards. It would give you a kinetic graph with delta values over time.
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