Hi som

It depends on 2 parameters;

First and most important being the hardware of your system. Better graphics card, , memory and processor is an advantage.

and Secondly it depends on the time(ns) you have put the simulation for.

Generally,with medium range hardware and simulation for 60 (ns) it  may take around 2-3 days.

I hope it helps.

It depends on the following factors:

a) The configuration of the system you are working with.

b) The size of the protein of interest.

c) Simulation time required to converge the RMSD of the protein.

Thanks 

Mohsin Yousuf Lone

Rajesh Pal

Mallikarjuna Rao Pichika