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Questions related from Rajesh Pal
We are trying to find the biological correlation between miRNA and certain genes. We found the general correlation through IPA (Ingenuity Pathway Analysis). Thank you for your inputs!
06 June 2019 6,985 6 View
I have mi-RNA sequencing data, where my 3 prime adapter is attached with 12 Nucleotide UMI Sequence (in random manner) along with Reverse Transcriptase primer and Universal Adapter Overall...
01 January 2019 647 5 View
I found an explanation in Schrodinger's knowledge base but i am not sure how to run the python scripts in Ubuntu. If possible kindly suggest an easy way. Huge Thanks
09 September 2018 7,891 3 View
I have a transcription factor protein X and X has a co-activator protein Y. XY bind to the DNA and downstream expression of proteins occur. Now I block the activity of X through inhibitor but dont...
08 August 2018 6,460 7 View
Kindly help me interpreting the graph. I am not sure if the ligand is still intact with protein or it has diffused away.
07 July 2018 2,032 6 View
I want to study the dynamics of ABC transporters along with a peptide molecule which in physiological conditions passes through the transporter. I am clueless how to set the peptide molecule in to...
06 June 2018 6,122 5 View
I have following doubts in Gromacs ,and want to know if these things are normal? or i am doing something wrong? 1) The protein is outside the solv box ( picture 1). 2) while i am running...
02 February 2018 7,816 5 View
Hello awesome people, I am new to GROMACS and i have been practicing with different tutorials available online. I successfully ran 1ns simulations. I ran couple of simulations with mdp files as...
02 February 2018 3,616 4 View
I want to perform protein-protein docking .Please suggest me some software's which can find active site by itself and dock the protein. I have tried HADDOCK but u need to provide active sites in...
09 September 2017 4,674 3 View
I have docked two proteins using patchdock but i am not able to view the P-P interaction in PIC calculator. I doubt there must be something wrong with the PDB files that i have given as input....
09 September 2017 9,980 8 View
We know that most of the major drugs and antibiotics resistance are due to the poor treatment practices. Thus, we search for new drug targets and new drugs. If the similar trend follows we run out...
08 August 2017 8,388 2 View
I have been isolating plasmid manually for the last few weeks using PCI method but i never got results. tried tons of protocols available online but i dont get it where i am going wrong. Even if i...
04 April 2017 620 5 View
Does the small letter in front of every different types of RNA have any significance
03 March 2017 4,177 0 View
I don't like the idea that you have to perform gel electrophoresis again n again to check the presence of the gene of interest. is there any alternate method to check it rapidly just like color...
03 March 2017 727 10 View
Thank you !!
01 January 2017 4,049 2 View
I have downloaded an sdf file from zinc but how do i get to know how many molecules are there in a single file, is there any particular software to see it?
10 October 2016 4,184 0 View
