How much minimal sample in animal model ex:rat for research? are there calculation?if you just one for control and one for treatment (just 2 groups)?
Are there the calculation or reference journal or books?
thanks for your answer
you will need at least 5 groups; 3 different dosages, 1 control positive, 1 control neg
I agree with Ikhtifar Rafi, you need at least 5 of them, but if you are doing preliminary analysis you can use one for positive, one for negative and one experimental group. After that you need to add more groups.
Also doses should be estimated based on previous similar researches or based on you own experience in experiments (or your supervisor).
Get a hold of a basic statistics text. You need to understand basic probabilities so that you know how many animals will be needed to give your experiment adequate power. You can't simply guess a number of animals, certainly your animal care committee will expect to see some sort of justification for your animal numbers.
I agree with Elizabeth, you must have at least 5 animals per group! In order to have some amount of data that you can process statistically further.
I agree with Elizabeth and Nikola ,at least you need 5 animal per group to perform an experiment ,for ethical and statistical reasons
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