I want to study effect of particular protein of PMN on parasite load in mice. In this set of experiment I am planning to adoptively transfer PMNs from wild type mice into parasite infected knockout mice. Then I want to compare parasite load between non adoptively transfer vs adoptively transfer vs control wild type mice. Please help me in executing answer to this problem.
Fang Yafei
Was your experiment going well? I am also conducting neutrophil adoptive transfer experiments, but I found that after injecting neutrophils from WT mice into KO mice that had depleted neutrophils, the circulating WT neutrophils in the KO mice quickly disappeared. I would like to ask if you have encountered similar problems and how to solve them?
0 votes
0 thanks
- Badges
- Science topic
- Similar topics
- Biological Science
- Immunology
- Antibodies
More Durgesh Pitale's questions See All
Similar questions and discussions