it depends on the complexity of your molecule. It could take 5 min for a single organic molecule to hours if you setup the superposition over the surface of several properties, such as electron density, Voids, Viewing down arbitrary crystal directions, rather than just the crystallographic a, b, and c axis, the configuration of the number of decimal places in the interaction energies window and so on.
As more properties you set up at once to be calculated, the longer it will take.
Another time-consuming procedure is to calculate the overall molecule surface rather than a specific part of the interest.