How gliosis inhibit axon regeneration?

More Dewan Md. Sumsuzzman's questions See All

How to handle missing data using multiple imputation in STATA?

Hi! How to handle missing data using multiple imputation in STATA?

03 August 2020 5,530 4 View

How To Drive a Culture of Experimentation For Effective AI (Artificial Intelligence)/ML (Machine Learning)?

Hi! There. How To Drive a Culture of Experimentation For Effective AI (Artificial Intelligence)/ML (Machine Learning)?

02 August 2020 474 4 View

What are the limitations of maximum likelihood estimation procedures when a majority of the observations are below the limit of detection?

Hi! there. What are the limitations of maximum likelihood estimation procedures when a majority of the observations are below the limit of detection?

02 August 2020 9,391 4 View

How to improve massively imbalanced datasets in machine learning with synthetic data?

Handling imbalanced datasets in machine learning is a difficult challenge, and can include topics such as payment fraud, diagnosing cancer or disease, and even cybersecurity attacks. How to...

28 July 2020 412 14 View

How to perform Stepwise Regression in R or STATA?

Hi!there. How to perform Stepwise Regression in R or STATA?

20 July 2020 1,093 8 View

How can I increase the accuracy of my linear regression?

Hi there. I have a machine learning project with python by using a scikit-learn library. I have two separate datasets for training and testing and I try to do linear regression. How can I...

20 July 2020 6,131 18 View

What are the differences between data profiling and data mining?

20 July 2020 1,477 16 View

What are the challenges in bridging data science, machine learning, and Accounting and Auditing?

14 July 2020 9,721 14 View

What are the drawbacks of Using Data Mining Softwares like-Sisense, Oracle Data Mining, RapidMiner when doing qualitative research?

Currently, I am working on coding the Intellectual capital information disclosed in the annual report of the organizations. There are many variables in the literature of intellectual capital and...

25 May 2020 1,855 10 View

Why does MODIS provide land cover product produced by itself?

MODIS has surface reflectance product too from where we can produce land cover output after supervised classification. From my knowledge of concern Landsat, Sentinel etc. only provide surface...

10 March 2020 8,283 3 View

What questions should i include in my questionnaire?

I am writing my dissertation, about adults who trained at elite status in their youth, i am constructing a questionnaire with the goal of seeing, how many sustained injury, how many sustained...

28 January 2021 4,787 3 View

Does the pre-synaptic neuron location in a cortical map influences the spatial position of its synapses in the dendrite of the downstream neuron?

Are functional maps in the cortex used by the brain to carry out computations or are they just a byproduct of wiring minimization? A key element to answer this question is to know if, when...

26 January 2021 1,118 8 View

Do drugs that are injected i.t in rats reach the supraspinal system and how long does it take to clear them from spinal cord?

I am injecting intrathecally (between L5-L6) , in rats, cannabinoid analgesics and I was wondering if they can reach the brain and have effects there as well ? Also I need to pretreat with...

07 January 2021 5,397 4 View

What's the reasonable loading control of nuclear protein in acute injury?

What's the reasonable loading control of nuclear protein in acute injury? Is HDAC1 or Histone H3 a resonable loading control of nuclear protein in acute injury model? How to explain total my total...

06 January 2021 1,607 2 View

Can we reuse the liquid desiccants once the dehumidification experiment is performed? can we store and reuse?

Liquid desiccants are used in our research work. Can we resuse it once we regenerate it.

05 January 2021 1,986 0 View

After cellulose is regenerated in water, a cellulose hydrogel is formed. I want to know if there is crystallinity inside the the hydrogel?

After cellulose is dissolved and regenerated in water, a regenerated cellulose hydrogel is formed. I want to know if there is crystallinity inside the hydrogel, or it will not crystallize until it...

04 January 2021 7,466 4 View

How do I post details of my new book?

Barracks, Forts and Ramparts: Regeneration Challenges for Portsmouth Harbour's Defence Heritage, by Celia Clark with Martin Marks OBE. Tricorn Books 2020. ISBN 9781912821648. 450 pages,...

30 December 2020 2,872 1 View

Pearsons correlation sample size HELP?

I'm conducting a correlational study about "is there a relationship between depression, acceptance and quality of life among spinal cord injury patient?" But I am having an issue determining the...

06 November 2020 9,798 10 View

Is there some specific drug to induce injury only in muscle fibers without affecting peripheral nerves?

I would like to induce injury in skeletal muscle fibers to study muscle regeneration but I would like to preserve nerve terminals intact. Could it be possible? Is there some specific drug? Thank...

30 October 2020 9,077 4 View

I'm looking for questionnaires to use to determine an athletes mental health after injury. What questionnaires would you recommend best fits??

I'm going into my final year as an undergrad Psychology student and I'm about to embark on my dissertation. I am looking to do my dissertation on sport psychology, looking at the impact of injury...

07 October 2020 8,220 4 View

Hércules Rezende Freitas

Dear Dewan,

I believe these works could help you in this matter:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693386/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984950/

http://www.sciencedirect.com/science/article/pii/S0925443915003531

https://www.nature.com/articles/nrn1326

Sincerely,

Hércules Freitas

Jill Miotke

Hercules has provided some of the classic reviews for the glial scar field.

However, in addition to the inhibitory nature of the glial scar, CNS axon regeneration is also inhibited due to developmental changes in the neurons themselves. The links below are to a couple of recent reviews:

Article An integrin approach to axon regeneration

Article Integrin signalling and traffic during axon growth and regeneration

These are just suggestions as to where to start your reading.

Best,

Jill

Please note, RG changed my links to the abstracts in PubMed to the articles in RG itself. I did not do this, and I am not trying to evade copyright protection of these articles.

Hercules, how did you get your links to stay as the original PubMed Central links? Inquiring minds want to know!