Surgical mesh implant in mid-urethral sling surgery can result in histopathological changes in the anterior vaginal wall, including dystrophic calcification. How frequently does dystrophic calcification occurs following mid-urethral sling surgery?
I have done thousands of slings and I have never seen calcification.You would need to implant the tape into the bone to get calcification. SOme very early slings were, in fact, implanted into the piosterior surface of the symphysis.
What we do see, and this is what the MUS operation is based on, is tissue reaction to create new collagen to reinforce the damaged or overstretched pubourethral ligaments.
Our experimental animal studies showed that there is wide variation in the amount of tissue reaction. SOmetimes the reaction can be sufficiently severe to cause a non-sterile abscess, sometimes many years after implantation.
It used to be in 1-2%, but with improvement in tape technology, this complication is now somewhat rare.
The other thing to watch out for, is urinary retention occurring 20-30 years later. I have seen everal of these and the tape needs to be cut. The reason for this is that the collagen changes with age. It contracts and becomes stiffer .
Thanks so much for taking the time to answer my question! In women with urine retention, did you also notice or had cases of sexual dysfunction? In fact, do you believe that the MUS procedure can lead to sexual dysfunction in female patients?
No. Never. In fact if you get a patient who loses urine during intercourse "post-coital incontinence", you can cure her with a MUS.
The man can get what some call "hispareunia" when there is protrusion of the tape in the vagina. The man feels a grating feeling and may even have trauma on his penis.
This is not a big issue. Just pull the loop of the tape down, press a scissors down to depress the vagina around each end of the loop as it enters the vagina and snip.