Depends on the type of data and type and details of Infomed consent taken from patients and the "every possible use" of that data by central repository, a large of number of ethical issues arise from this situation, it might violate patient's autonomy, privacy and confidentiality and social stigmatization of a particular community is also possible ( precedence available in history) . I think a good Ethical Review Committee should seriously look into this and thoroughly investigate it before giving permission to handover such data.