How does the surface chemistry of green-synthesized nanoparticles affect their interaction with biological systems in drug delivery or medical applications?
The interactions of nanoparticles with the medium will depend on the surface functionalization. The presence of coating or capping agents on their surface can also contribute to their stabilization and functionality (e.g. solubility, biocompatibility, host-receptor interactions, biological targeting, etc).
The role of surface chemistry in green-synthesized nanoparticles lies in mediating the interactions of harmful substances (e.g., drugs, toxins) on the nanoparticle surface .
Surface chemistry examines:
The role of catalysts and ligands.
The effects of surface area and porosity on reactions.
Example: Drug Loading
Porous/Biomolecule-Coated Surfaces: Enable high drug-loading capacity (e.g., polyphenol-stabilized NPs for hydrophobic drugs).
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