I use H2 (gas) on Pd to deprotect a Cbz group on a system that has a thiazole ring. Due to the presence of sulfur in the thiazole ring I have to use high amounts of Pd to get the reaction done. I believe that sulfur just coordinates to Pd and blocks its activity. Am I right? Does anyone know this "poisoning" mechanism?
Acctualy sulfur in the form of thiophene and thiazole ( Organic sulpher compounds) can deactivate Pt and Pd catalyst. I have the same experience on Pt/Pd catalyst in hydrogenation of DNT. for more information please follow this link: Article Heterogeneous Catalyst Deactivation and Regeneration: A Review
Sulfur is a poison of pd catalyst. You can enhance the activity by adding another metal for catalyst as promotor in bimwtallic form.
- Badges
- Science topic
- Similar topics
- Engineering
- Petroleum Engineering
- Gas