how does COVID19 affect blood group A patients more compared to O as per the recently published data? What can be the reason?
People with blood group A is 20% more likely to contract COVID-19 compared to blood group O> For how and why have a look at the attached articles.
1. Preprint The ABO blood group locus and a chromosome 3 gene cluster as...
2. Preprint Relationship between the ABO Blood Group and the COVID-19 Su...
See the different reality in different sites. It needs extra time to make a conclusion.
COVID-19 and Blood Type
Study finds no relationship between blood type and severity of COVID-19
By MGH NEWS AND PUBLIC AFFAIRS, July 17, 2020 Research
HARVARD MEDICAL SCHOOL (https://hms.harvard.edu/news/covid-19-blood-type)
Blood type is not associated with a severe worsening of symptoms in people who have tested positive for COVID-19, report Harvard Medical School researchers based at Massachusetts General Hospital.
Their findings, published in the Annals of Hematology, dispel previous reports that suggested a correlation between certain blood types and COVID-19.
The study did find, however, that symptomatic individuals with blood types B and AB who were Rh positive were more likely to test positive for COVID-19, while those with blood type O were less likely to test positive.
Testing the association between blood type and COVID-19 infection, intubation, and death
Michael Zietz and Nicholas P. Tatonetti
Preprint Testing the association between blood type and COVID-19 infe...
A recent study of patients in China discovered an association between ABO blood type and SARS-CoV-2 infection status by comparing COVID-19 patients with the general population. Whether blood type is associated with increased COVID-19 morbidity or mortality remains unknown. We used observational healthcare data on 1559 individuals tested for SARS-CoV-2 (682 COV+) with known blood type in the New York Presbyterian (NYP) hospital system to assess the association between ABO+Rh blood type and SARS-CoV-2 infection status, intubation, and death. We found a higher proportion of blood group A and a lower proportion of blood group O among COV+ patients compared to COV−, though in both cases the result is significant only in Rh positive blood types. We show that the effect of blood type is not explained by risk factors we considered (age, sex, hypertension, diabetes mellitus, overweight status, and chronic cardiovascular and lung disorders).
The immune systems of people with Type O blood already have antibodies for both A and B, their bodies are more equipped to identify foreign proteins—including those on the surface of viruses, also, Some of the conditions observed in COVID-19 patients—including blood clots, strokes and thromboembolisms—may also vary in severity based on blood type, adding another possible explanation. https://www.tmc.edu/news/2020/06/blood-type-may-affect-covid-19-outcomes-study-shows/
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