there is an interesting publication that relates to your first question, "SkBQ - Prooxidant Addressed to Mitochondria" by Vyssokikh et al., published in Biochemistry (Mosc). 2013 (doi: 10.1134/S0006297913120079). The authors describe effects of the pro-oxidant SkBQ at the cellular level. Maybe this publication (and related works from the group of V. Skulachev) can help you to get a better understanding.