You can use R:
https://cran.r-project.org/
With R installed, you can use a free RStudio version as an IDE.
https://www.rstudio.com/
And the package called metafor, has functions to calculate meta-regression
https://cran.r-project.org/web/packages/metafor/metafor.pdf
Best Regards
R is a great source for almost all statistical analyses.
For a stand-alone meta analysis, RevMan 5 is a great tool to run meta-analysis. It's also pretty easy to use.
It depends on how in depth the stats you are aiming to do are. The simplest is Revman from Cochrane. It's free if you download the version to produce cochrane reviews, but you can just use parts of it to do meta-analyses for non-cochrane reviews.
http://community.cochrane.org/tools/review-production-tools/revman-5/revman-5-download
This article https://toptipbio.com/free-meta-analysis-software/ presents 13 Best Free Meta-Analysis Software to Use. Most of them do not require coding knowledge which is associated with R.
https://toptipbio.com/free-meta-analysis-software/
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