I am interested in comparing the fecal samples of Nomotensive, Pre-Hypertensive and Hypertensive patients through the findings from genesequencing and culture. The gene sequencing will be sample from the lab work while the culture process will involve, serial dilution, culturing the sample on different plates and observations will be taken.
How can I determine the sample size before going out to carry the experiment? Kindly help please.
Hello Oladapo,
There is a wikipedia article on this vey topic which you might wish to read. If you seacrh with the terms „sample size determination“ in the internet, you will find several good explanations, what to do……
In addition, probabaly, the paper written by Dell, Holleran & Ramakrishnan on „Sample Size Determination“, published in ILAR 2002, pages 207-13 might be hepful.
Good luck in your research & studies
SR
If you know the mean and standard deviations, then something like G*Power could help; Universität Düsseldorf: G*Power (hhu.de).
You could read published work and take a guess at the right (publishable) sample size, or you could run a preliminary trial designed to estimate the appropriate sample size. There are economic and personal costs to having a large sample size that needs to be weighed against the risk of project failure costs if your sample size is too small.
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