How do I calculate SSMD in a HTS?

How to compare two groups with only two measurements?

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03 March 2021 8,796 3 View

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How to increase a model accuracy ?

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Do I need to do linear regression before running mediation analysis using PROCESS MACRO by Hayes ?

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Sample dilution for quantitative analysis using ELISA?

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Is There Any Feasible Method To Test Fluorescent Compounds Other Than Fluorescence Spectrometers ??

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How to calculate average trend in maximum annual NDVI from MODIS?

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Yaoyong Li

Hi Paul,

how many replicates do you have? SSMD needs at least two replicates because it need calculate the standard deviations.

It looks that your data is similar to our data in the PNAS paper in http://www.pnas.org/content/110/30/12426.full. If you have replicates, I think that you can use the SSMD method on your data as what we used (for details see the statistical analysis section of the supplementary document in http://www.pnas.org/content/suppl/2013/07/08/1305207110.DCSupplemental/sapp.pdf.

Yaoyong

Ron Geller

Hi,

In case it is of help to anyone, I find this paper quite useful for understanding the SSMD calculation under different conditions. Article Illustration of SSMD, z Score, SSMD*, z* Score, and t Statis...