I received nanoparticles.
After drying it will be very difficult to redisperse. Are you sonicating the sample? Were the silica particles protected before drying?
Adjusting the pH and sonication followed by vortexing might help.
If sonication will favor the release of the drug then the system is not properly designed. Anyway any peg derived surfactant might help. Do not dry the sample if possible.
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