As a general rule, mission drift is measured by the amount of money per credit. The bigger the credit, the wealthier the client. That is easily measured through the average credit of an MFI. There are several papers on the subject because it is a very important matter in microfinance, for instance Armendáriz, B. y Szafarz, A. (2009): “Microfinance Mission drift”. You can also see Rosemberg´s paper on measures and indexes for this use.