Over the past six months, a patient with hereditary desminopathy (Thr341Pro DES mutation in the heterozygous state) has a 1.6-fold increase in the level of the pro-inflammatory cytokine interleukin-6 to a value of 8.77 pg / ml (
You can bring it down by introducing anti inflammatory cytokine especially the ones that are bio markers of the disease.
Dear Viacheslav,
You can check the option of anti IL-6 or IL-6 receptor therapy. IL-6 and other cytokines are estimated in serum or plasma?
Thanks
Dear Emmanuel Ifeanyi Obeagu and Sukhvinder Singh, thank you very much for your answers. IL-6 and other cytokines were evaluated in serum. To reduce IL-6, which anti-inflammatory cytokine can be used - Il-10 or another?
Tocilizumab it is anti IL-6 it binds to IL-6 receptor it was used in rheumatoid arthritis in a dose 2-4-8/kg Iv
I am not very relative, but to the best of my knowledge IL-10 is the best antidote, similarly HemeOxygenase 1 can also be considered.
After 4 months, a patient with hereditary desminopathy (Thr341Pro DES mutation in the heterozygous state) had a 2-fold decrease in the serum level of the proinflammatory cytokine IL-6 to a value of 4.27 pg / ml (norm
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