In a patient with hereditary desminopathy (Thr341Pro DES mutation in a heterozygous state) with disease progression over the past 7 years, the level of residual nitrogen in the blood increased 1.5 times to 24.2 mmol / L (normal 14-28 mmol / L), and the level blood urea increased 1.24 times to 5.7 mmol / L (normal 2.5 - 8.32 mmol / L). Could this worsen the condition with desminopathy?
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