Hi ulrich . I want to fuse a blood cell to cancer cell . How can i do this method in vivo ? 

thank you for your answer . 

Hi, Mohammadreza,

I work with electroporation. Electrofusion would be a solution for you but the equipment is quite expensive unless you have coleagues that can design an electroporator. In vivo it's hard to imagine the process but in-vitro you would succeed using a chip for fusion and adequate electrofusion aparatus. How will you be able to see if you fused those cells in vivo or not? The problem is you have a flowing system in-vivo. For electrofusion you need some time for cells to get closer to be able to fuse them. That probably would be a problam. But if you talk about low flow ratio body parts in the living organism then you should use plate electrodes and appropriate pulses. There is a possibility you will succeed but you need to read about electrofusion more. I'm not that strong in electrofusion field. 

Good luck

Hi , did you recommend any specific equipment for electrofusion? I tried BTX Hybrimune from Harvard Apparatus but they charge annualy a fee of USD 15000.00. too expensive.

anyone can help indicating other equipments?

thanks in advance