I did not get a product sheet with it so i googled other product sheets for cisplatin(Which has the same molecular formula) and they mentioned I can dissolve it with DMF with "gentle heating".
I'm trying to contact the company but meanwhile does anyone how to exactly dissolve this drug? Do i need to vortex it? is it okay to be handled in at Room temperature for the duration of me dissolving it as it does mention "gentle heating"but they do not mention what is considered as "gentle heating"
https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/Product_Information_Sheet/1/p4394pis.pdf
Dear Sarah,
Take a look at a related post (link below), maybe some of the answers could be of help.
https://www.researchgate.net/post/Does_anyone_know_how_stable_cisplatin_is_if_I_dissolve_it_in_PBS_and_keep_it_at-20_C_as_a_stock_solution
Also, please, be ware that cisplatin loses some or all of its activity when dissolved in solvents such as DMSO or DMF that form complexes with Pt2+. A paper that explicitly dealt with that:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508678/
Best regards,
Niko
i have a question regarding solubility of cisplatin. i am preparing nanoparticles of chitosan containing chitosan, which i dissolve in 0.1% acetic acid. not need suitable solvent for cisplatin
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