Dear Vijayji,

You can determine and analyse the cis acting element in gene which encode for Lipoxygenase protein in Homo sapiens.  

u can retrieve nucleotide sequence of gene encode for Lipoxygenase  instead of protein sequence from suitable resources.

after sequence retrieval you can use DiRE tool for determination & analysis of cis acting elements.

http://dire.dcode.org/

Dear Vijayji,

You can determine and analyse the cis acting element in gene which encode for Lipoxygenase protein in Homo sapiens.  

u can retrieve nucleotide sequence of gene encode for Lipoxygenase  instead of protein sequence from suitable resources.

after sequence retrieval you can use DiRE tool for determination & analysis of cis acting elements.

http://dire.dcode.org/

you can use http://www.biomart.org/biomart/martview/070a97a02deb27e802d6d23cdf49039b

for retrieve any sequence (promoter) from varies sequence IDs. After that using a suitable cis acting element database, you analyse cis acting elements of your protein.

One useful place to start is GeneCards:

http://www.genecards.org/

Type "lipoxygenase" into the Search box and click submit.  You will see a list of official gene names containing that word and also other related genes.  Click on the one of your interest.  This will take you to a page with links to numerous resources providing further information on that gene.  In the "Genomic Views" section look for the link that reads "gene promoter sequence"

You can also search at the Eukaryotic promoter database with the gene name that you found at GeneCards.  The link is:  http://epd.vital-it.ch/

The UCSC genome browser also has substantial gene annotations:

http://genome.ucsc.edu/cgi-bin/hgGateway

Again, enter the official gene name that you found at GeneCards into the search box and click submit.

Thanks David 

Another great online utility that I just found is at:

http://biogrid-head.engr.uconn.edu/lasagna_search/

It has lots of capabilities and flexibilities.  Promoter sequences can be retrieved "automatically" from a variety of species.  You can choose which TF motifs you wish to search and also the significance "cut-off" value for reporting matches.  You even have the option of entering a motif matrix of your own in addition to choosing from a wide variety of pre-defined matrices or sets of matrices.

Reference publications are at:

http://bioinformatics.oxfordjournals.org/content/30/13/1923.full

http://www.biotechniques.com/multimedia/archive/00190/BTN_A_000113999_O_190213a.pdf

The latter has a more complete description of functionalities.

Dear David,Unable to access both of the publication referenced by you. Can you send me it via email? Please